Diabetes mellitus: Symptoms classification, risk factor and complications
Introduction
Classification (4):
1.
Type
1 diabetes mellitus
Ø Immune mediated
Ø Idiopathic
2. Type 2 diabetes mellitu
3. Other
specific types of diabetes
Ø Genetic defects of islet ß-cell function
Ø Genetic defects of insulin
action
Ø Diseases of the exocrine
pancreas
Ø Endocrinopathies
Ø Drug- or chemical- induced
diabetes
Ø Infections
Ø Uncommon forms of diabetes
Ø Other genetic syndromes
4. Gestational diabetes
mellitus
Diabetes mellitus risk factors
1. Diabetes mellitus type I risk
factors include:
Ø Family
history.
Ø Infections
or diseases of the pancreas.
2. Diabetes mellitus type 2 risk factor include:
Ø Obesity
and overweight
Ø Hypertension
Ø Hypertriglyceridemia
Ø Decreased
physical activity
Ø Family
history
Ø Old
age
Ø Smoking
Symptoms
Symptoms
of diabetes mellitus include
- Polyuria
- Polydipsia
- Weight loss
- Polyphagia
- Fatigue
- Skin disorders
- Late healing wounds
Complications of diabetes mellitus
1. Acute complications
Ø Hypoglycemia
Ø Diabetes Ketoacidosis (DKA)
Ø Hyperglycemic hyperosmolar state (HHS)
2. Chronic
complications:
A. Micro vascular complications
Ø Diabetic retinopathy
Ø Diabetic nephropathy
Ø Diabetic neuropathy
B. Macrovascular
disease
3. Other
complications and associated conditions:
Ø Non-alcoholic fatty liver disease.
Ø Infections seen in patients with diabetes.
Ø Limited joint mobility 5.
References
1.
American
Diabetes Association, Diagnosis and Classification of Diabetes
Mellitus.
DIABETES CARE 2005; 28: S37 ̶ S42.
2.
Wise
J. Type 1 diabetes is still linked to lower life expectancy. BMJ 2016;1.
3.
English
E, Lenters-Westra E. HbA1c method performance: the great success story of
global standardization. Crit Rev Clin Lab Sci 2018; 55:408-19.
4.
World
Health Organization, Laboratory Diagnosis and Monitoring of Diabetes Mellitus
2002.
5.
Baynes
HW. Classification, Pathophysiology, Diagnosis and Management of Diabetes
Mellitus. J Diabetes Metab; 2015: 6: 541.
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