كيفية تحضير كوب الشاي الاخضر: طريقة عمل كوب الشاي الاخضر

Prostatic enzyme (Acid phosphatase, ACP)

Acid phosphatase (ACP) belongs to phosphatase enzymes which are a hydrolase. The major difference between ACP and ALP is the pH of the reaction. Acid phosphatase is an enzyme which hydrolyses phosphate at acidic pH (optimal pH is 5.0).

Sources of acid phosphatase

ACP activity is found in the prostate, bone, liver, spleen, kidney, erythrocytes, and platelets. The prostate is the richest source. The estimation of acid phosphatase is used in the diagnosis of prostatic carcinoma.

Diagnostic Significance

High acid phosphatase occurs in:

1. Prostatic carcinoma, particularly metastatic carcinoma of the prostate.

2. Other prostatic conditions

Ø  Hyperplasia of the prostate.

Ø  Prostatic surgery.

Ø   Acute retention of urine.

Ø  Passage of catheter leads to pressure on prostatic cells.

Ø  Following rectal examination and prostate massage.

3. Bone disease. Activity has been shown to be associated with the osteoclasts.

Ø  Paget’s disease

Ø  Breast cancer with bone metastases.

Ø  Gaucher’s disease, in which there is an infiltration of bone marrow and other tissue by Gaucher cells rich in ACP activity.

4. Thrombocytopenia resulting from excessive platelet destruction from idiopathic

thrombocytopenic purpura.

5. Polycythemia