كيفية تحضير كوب الشاي الاخضر: طريقة عمل كوب الشاي الاخضر

 Hepatic synthetic function evaluation

Introduction:

The liver has role in the synthesis of plasma proteins, coagulation factors, albumin, Urea and some extent of α and β-globulins.

The liver (in fasting state) produces glucose from non-carbohydrate substances through gluconeogenesis as well as liver synthesizes cholesterol so fasting blood sugar and serum total cholesterol may be decreased in severe liver diseases (e.g. liver cirrhosis), therefore fasting blood sugar and serum total cholesterol can be used for hepatic synthetic function evaluation in severe liver diseases.

Defect of hepatic synthetic functions can lead to increased prothrombin time, decreased fasting blood glucose, low blood urea and low serum total cholesterol.

The measurement of plasma albumin and prothrombin time may be used to assess liver functions e.g. cirrhosis impairs albumin and prothrombin synthesis.

The serum total proteins and serum albumin estimation is most common for evaluation of hepatic synthetic functions and diagnosis and follow up of hepatic synthetic functions defects but there are other causes for serum total protein and albumin abnormalities.

Serum total protein abnormalities

•       Malnutrition (e.g. kwashiorkor).
•     Malabsorption.
•      Liver diseases.
•     Overhydration.
•       Loss of blood.
•     Sprue.
•     Renal failure.
•     Nephrotic syndrome.
•     Severe burns.

 

Serum albumin abnormalities

      1. Nephrotic syndrome

2. Protein-losing enteropathies

3. Burns

4. Malnutrition 

5.Malabsorption

6. Liver disease